|#1||Raindrops Keep Falling On My Head|
While Meredith and Cristina discuss their shortcomings at the Emerald City Bar, Joe the bartender collapses. Dr. Webber recovers from his surgery and asks George to be his 'eyes and ears'. Dr. Addison Shepherd arrives in Seattle to join her husband at the hospital, causing an explanation to Meredith.
|#2||Enough is Enough (No More Tears)|
Mrs. Webber returns from vacation to help her husband recuperate from his surgery. George continues to be associated with nurse Olivia but still has a crush on Meredith. A car crash brings a family into the hospital which causes a liver transplant debate between the father and son. Dr. Bailey deals with an odd surgery.
|#3||Make Me Lose Control|
Meredith's secrets are made painfully public when her mother is brought to Seattle Grace for a surgical procedure. Meanwhile, shocking news about Cristina’s health is brought out into the open.
|#4||Deny, Deny, Deny|
As Cristina tries to recover, she proves to be a very difficult patient, and a visit from her mother doesn't improve her demeanor at all. Meredith's mother, Dr. Ellis Grey, has the hospital staff running in circles.
|#5||Bring the Pain|
Meredith and Dr. Shepherd have to use more than medicine when a young Hmong woman’s traditional, religious father forbids her to have a life-saving operation. Meanwhile, George and Alex are forced to perform surgery under less than ideal conditions in an attempt to save a patient’s life. Derek must make a decision between Meredith and Addison.
|#6||Into You Like a Train|
While Meredith nervously awaits Derek's decision, her angst is interrupted by a train crash that brings several seriously injured patients to the hospital, including Bonnie and Tom, a pair of passengers who’ve been impaled on a metal pole. Addison Shepherd sees great potential in Izzie, who must decide whether her loyalty as Meredith’s friend outweighs professional gain.
|#7||Something to Talk About|
Cristina, Izzie, and Meredith aggressively pursue the case of Shane, a male patient who seems to have a hysterical pregnancy, which fascinates them and the entire medical staff; and a sheltered young patient inspires Alex to better express his feelings for Izzie.
|#8||Let It Be|
Derek and Addison Shepherd’s professional relationship is challenged when their closest friends come to Seattle Grace seeking a radical, preemptive operation to avoid breast and ovarian cancer. Cristina and Dr. Burke go on a date.
|#9||Thanks for the Memories|
The Thanksgiving holiday is more difficult for the interns and residents than any of them is willing to admit, as Izzie plans a big dinner at Meredith’s -- but it remains to be seen who among the invited guests will actually show up. Meanwhile, George endures the O’Malley tradition of hunting turkeys with his less-than-sophisticated family, and Meredith treats a patient who’s been in a vegetative state for 16 years.
|#10||Much too Much|
Meredith is mortified when her “one night stand” shows up at the hospital suffering from priapism and needing medical attention. A patient carrying quintuplets is overwhelmed by numerous medical issues as she navigates her high-risk pregnancy. Alex begins to frustrate Izzie.
|#11||Owner of a Lonely Heart|
Cristina Yang has little sympathy for a prison inmate who jeopardizes her health just to get out of solitary confinement. Meanwhile, the interns all keep careful watch on the family of premature quintuplets with a variety of serious health challenges.
|#12||Grandma Got Run Over By a Reindeer|
A young boy needs a heart transplant but doesn’t seem to want it, and his treatment causes Burke and Cristina to have philosophical differences. Meanwhile, when the interns rally to help Alex prepare to re-take his exam, Meredith has to remind Izzie of the true spirit of the Christmas holiday; and despite a reconciliation with his wife, Derek isn’t in a festive mood.
|#13||Begin the Begin|
Izzie seems to be getting over Alex when she shares an undeniable chemistry with Denny Duquette, a patient who’s awaiting a heart transplant, and George treats Bex, a young intersex patient.
|#14||Tell Me Sweet Little Lies|
The truth is in short supply as Meredith and Cristina lie to themselves and each other about the status of their relationships. George is given the unpleasant task of discharging an elderly patient who’s no longer sick, but refuses to leave the hospital; and Alex learns his fate after re-taking his medical exams.
|#15||Break on Through|
The nurses at Seattle Grace Hospital go on strike, leaving the doctors to fend for themselves; Meredith’s mistake in treating an elderly patient is brought to light by the patient’s friends. Izzie reveals a cherished secret to a pregnant teen.
|#16||It's the End of the World|
Meredith's fears that she is in for a bad day are realized when a medial case arrives at Seattle Grace that threatens the lives of everyone in the O.R..
|#17||(As We Know It)|
Despite the best efforts of the Seattle Grace staff, the code black situation escalates. Dr. Bailey gives birth in the midst of the circumstances.
Someone from Derek and Addison’s past arrives in Seattle and shakes things up. Meanwhile, Burke learns about Cristina’s secret and, after a visit with her mother, Meredith looks into more of her family’s dirty laundry.
|#19||What Have I Done to Deserve This?|
Meredith and George suddenly find themselves at odds at work. Meanwhile Bailey, although technically still on maternity leave, finds herself treating Addison for an unusual feminine issue, and Alex finds himself oddly jealous when Izzie pays more attention to Denny.
|#20||Band-Aid Covers the Bullet Hole|
After Dr. Bailey is called into surgery, Cristina is forced to watch baby Tucker for the remainder of the day. Meanwhile, George and Meredith are still on the outs as she confides in Derek with her problem. Izzie continues to warm up to Denny who is having problems breathing. George meets a new friend.
When a series of deaths occur at Seattle Grace, the uncanny events bring out the doctors' superstitious sides and make Izzie nervous about Denny's surgery. Meanwhile, Derek and Addison discuss making a more permanent living arrangement, and Richard treats a very special, old friend.
|#22||The Name of the Game|
George begins to overstay his welcome at Burke's apartment; Meredith learns a secret about her father; Bailey worries her colleagues will not treat her the same now that she's a mother; and Alex gets a lesson in bedside manners.
|#23||Blues for Sister Someone|
Izzie grills George about the personal details of his life, Addison takes Alex to task about a sensitive case, and Burke feels the pressure when he treats his musical hero.
The interns deal with a family involved in a car accident, Derek lets his emotions get the best of him, and Burke and Izzie make a new suggestion to Denny.
Victims of a workplace shooting fill the ER as Derek and Addison's marital tensions come to a head and Burke, Alex and Izzie fight for a heart for Denny.
|#26||Deterioration of the Fight or Flight Response|
Izzie and George attend to Denny as the pressure increases to find him a new heart, Cristina suddenly finds herself in charge of a Trauma Room, Dr. Webber's niece is rushed to the emergency room from her prom and Derek grapples with the realization that the life of a friend is in his hands.
|#27||Losing My Religion|
Dr. Webber goes into interrogation mode about Denny's condition. Callie confronts George about his feelings for her. Dr. Bailey forces the interns to throw a prom for Dr. Webber's niece. Meredith and Derek are forced to make a decision regarding their dog. A fight between the two results in a long awaited reunion.
Grey's Anatomy Season 2 Episode Guide Content licensed under the GNU Free Documentation License.