A 29-year old preschool teacher (guest star Robin Tunney) collapses in her classroom from a seizure. She is taken to Princeton-Plainsboro Teaching Hospital, where Dr. House and his team of experts struggle to solve the mystery. Another version of the pilot was to be aired in this slot, but 4 minutes of footage were cut out at the last minute. The unaired pilot was then released to specific magazines to promote the show.
A 16-year-old high school student, Dan (Scott Mechlowicz), starts suffering night terrors and frequent hallucinations after playing lacrosse at school. The parents take him to Dr. House after receiving a letter that he apparently sent and House starts a bet on whether they are his biological parents. Meanwhile, House must deal with a patient looking to set up a lawsuit and a mother who does not believe in vaccinations.
House and his team struggle to find out why a college student (Kevin Zegers) collapsed after having sex with his fiancée.
House's prediction that two sick babies is the beginning of something worse is dreadfully correct and he and his team quarantine the hospital's maternity ward as they try to determine the source of the illness.
|#5||Damned If You Do|
House's approach raises questions when he treats a nun for what he believes to be an allergy, and almost kills her.
|#6||The Socratic Method|
When a schizophrenic mother has a deep-vein thrombosis, a strange phone call causes House to question her sanity once again.
Two men are out jogging – one of them (guest star Dominic Purcell) returns home to his bedridden wife, who lashes out at him. Believing there is something wrong, she is sent to Princeton-Plainsboro, and when all the treatments fail, House concludes she has African sleeping sickness. However, neither the wife nor her husband have ever been to Africa. The woman will die without proper treatment, but neither one will also admit to having an affair.
House and his team investigate the mysterious poisoning of high-school student Matt Davis, until another teen is brought in with all of the same symptoms but almost nothing else in common with Matt.
When a legendary jazz musician collapses mid-session, House and his team run into technical difficulties treating the man, who has amyotrophic lateral sclerosis. House ignores the DNR order and ends up in court.
Dr. Foreman believes an uncooperative homeless woman is faking seizures to get a meal ticket at the hospital. But her situation strikes a chord with Dr. Wilson and he resolves to keep her from falling between the cracks. Meanwhile, House has an audience of two medical students who are learning how to do case studies.
While trying to figure out why a young patient will not stop bleeding after a car wreck, House accepts Cuddy's challenge and goes off Vicodin for a week in exchange for no clinic duty for a month. As House's withdrawal symptoms become severe, his methodology for his patient are more harsh and risky, and Foreman and Cameron are afraid he may not be thinking clearly enough to save the patient's life.
A severely broken arm reveals a bizarre case of bone loss and ends the comeback plans of major league pitcher Hank Wiggen. House suspects Hank – with a history of drug abuse – is lying about using steroids, as his condition worsens. When Hank's kidneys start to fail, his wife offers to donate hers, but she will have to abort her early pregnancy, something Hank does not want. Meanwhile, Foreman dates a pharmaceutical representative and House is stuck with an extra ticket to a monster truck rally.
After consulting an Ouija board, a young boy believes he is going to die, and is sent to Princeton-Plainsboro after suffering from pneumonia. Dr. Chase's estranged father (guest star Patrick Bauchau) comes to the hospital and helps House diagnose the kid.
Billionaire entrepreneur Edward Vogler donates $100 million to Princeton-Plainsboro and becomes the new Chairman of the Board. Vogler intends to turn the clinic into a profitable venue for his biotech venture and plans to eliminate House's financially draining department. Meanwhile, a businesswoman has it all – perfect life, perfect body, perfect job – until she finds herself inexplicably paralyzed. When he diagnoses her condition, House must risk his job and his medical license to save her.
House is placed under a court order to determine what is ailing a mobster due for federal testimony and the Witness Protection Program. The witness's brother, a lawyer, works against the team and the testimony when his brother is diagnosed with Hepatitis C. Cuddy continues to battle Vogler over House's importance to the hospital.
House and his team investigate an overweight ten-year-old girl who has a heart attack. Adding to his stress, Vogler demands House get rid of a member of his team.
A popular U.S. senator and presidential candidate succumbs to illness at a fundraiser and Vogler assigns House to his case. He also tells House he can keep his whole team if he endorses Vogler's pharmaceutical company. The Senator's initial diagnosis seems to point to AIDS, but House digs deeper for another answer. Meanwhile, he also handles a case of a woman who apparently gets pregnant without having sex.
|#18||Babies & Bathwater|
A pregnant woman arrives at the hospital with brain and kidney problems and House must contend with her condition and Vogler's eagerness to see the doctor removed by using the board members. The patient and her husband must decide between her life and their unborn child's, after the team discovers small cell lung cancer.
House fights off a meningitis outbreak and Cuddy gives his team an hour to produce results after he singles out a young patient who does not quite fit the criteria. House tries to get Cameron to return in the wake of Vogler's departure, but she demands House tell her why he really wants her back.
The teaching hospital buzzes with rumors of House's upcoming date with Cameron. After House is harsh to an awaiting clinic patient (guest star John Cho), the man develops a mysterious stroke. At the same time, House also deals with an elderly couple whose overactive sex life causes them problems.
House receives a visit from an ex-girlfriend, Stacy Warner, who seeks his help for her husband. Cuddy forces House to give a lecture to medical students on diagnosing patients and presents three scenarios, each with different reasons for their leg pain (with guest star Carmen Electra).
House diagnoses Mark, Stacy's husband, and although the tests do not indicate a condition and Mark claims to be fine outside of stomach pain, it appears his brain is dying, leaving House puzzled. When he comes to a potential diagnosis, he has to fight against Mark's wishes to get the proper test done.
House Season 1 Episode Guide Content licensed under the GNU Free Documentation License.